Inflammatory bronchial polyps associated with asthma: resolution with inhaled corticosteroid

Inflammatory bronchial polyps associated with asthma: resolution with inhaled corticosteroid.

In a 50 year old man who complained of cough and sputum, a small endobronchial tumour was found in the left main bronchus and was biopsied via bronchoscopy. The histological diagnosis was inflammatory polyp with marked infiltration of eosinophils. Six years later, the patient developed asthma. At the same time, another polyp was found in the posterior basal bronchus of the right lower lobe. The...

Pulmonary Artery Agenesis with Bronchial Asthma

Unilateral Pulmonary Artery Agenesis (UPAA) is a rare congenital anomaly during the 4 th  week of gestational age. It is defined as an absence of pulmonary parenchyma and its supporting artery. A 9-year-old girl was admitted to our hospital because of chronic cough. Chest examination showed a decrement in lung sound of right hemi-thorax with expiratory wheeze. Chest radiography (CXR) revealed a...

Inhaled corticosteroid dosage in asthma.

Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

BACKGROUND T regulatory (Treg) cells are important in balancing immune responses and dysregulation of Treg cells has been implicated in the pathogenesis of multiple disease states including asthma. In this study, our primary aim was to determine Treg cell frequency in the peripheral blood of children with and without asthma. The secondary aim was to explore the association between Treg cell fre...

Effects of Inhaled Glucocorticosteroids Treatment on Clinical and Eosinophilic Inflammatory Parameters in Patients with Bronchial Asthma

Inhaled glucocorticosteroids are the most efficient anti-inflamatory drugs used in asthma treatment that can bring the improvement of clinical symptoms as well as lung function. Eosinophils (Eo) are the key efector cells in asthmatic inflammation, and determination of their number and concentration of mediators which can bring about eosinophilic activationinterleukin-5 (IL-5) would contribute t...